Cardiac abnormalities in children with Kawasaki disease from an Algerian single center

N.Benali Khoudja

Background: coronary artery involvement during Kawasaki disease determines its prognosis. Other cardiac abnormalities can occur and are in the foreground.
Objective: To identify coronary and non-coronary cardiac abnormalities observed in children with Kawasaki disease(KD).
Materials and Methods: 32 children with KD are recorded from 2015 to 2025. The analysis concerned the clinical presentation, ECG and echocardiographic characteristics with attention to the coronary arteries and the evolution.
Results: We observed 11 (34.5%) children with typical KD, 10 (31%) with atypical KD and 11 (34.5%) with MIS-C, 5 of whom were in shock. Cardiac abnormalities were found in 15 (47%) patients: 6 with coronary artery abnormalities, 7 with acute myocarditis, 6 with valve regurgitation, 3 with pericardial effusion and 2 with ECG abnormalities of the prolounged PR . IVIG is used in 25 (78%) children, corticosteroids in 16 (50%), aspirin in 21 (65.5%). The outcome is favorable in 30 patients (93.7%), one patient developed a LMCA aneurysm that receives aspirin and one patient died with COVID-19 intestinal perforation.
Discussion: Most authors have described non-coronary heart abnormalities that are often resolved after well-conducted treatment, the most common being acute myocarditis, but it is coronary artery involvement that causes complications with the risk of sudden death.
Conclusion: cardiac abnormalities should be screened in any patient with KD. They help in the diagnosis and make the disease complicated if treatment is delayed.